Influence of circadian rhythms in tumorigenesis – Role of vanillic acid on liver cancer

Rhythmicity is observed in transcriptional expression of a wide range of clock-controlled genes which regulate a variety of normal cell functions like cell division and proliferation. The human circadian timing system functions to co-ordinate humoral, physiological, and behavioral mechanism to promote sleep and waking behavior. The rhythms are generated by neural structures in the hypothalamus that function as a biological clock. Modern...