Continuous glucose monitoring using a microneedle array sensor coupled with a wireless signal transmitter

A minimally invasive wireless biosensor was developed for glucose monitoring using human blood. The sensor probe was shaped in a microneedle array with a cyclic olefin copolymer. FAD-glucose oxidase (GOx) was covalently bound to a terthiophene carboxylic acid (TCA) monomer followed by electropolymerization on a gold-coated microneedle (AuMN) array using the potential cycling method (AuMN/pTCA-GOx). The formation of the sensing probe layer on the...