Insulin Delivery: Erythrocyte‐Membrane‐Camouflaged Nanoplatform for Intravenous Glucose‐Responsive Insulin Delivery (Adv. Funct. Mater. 41/2018)

Yu Fu; Wei Liu; Luyao Wang; Bi‐yue Zhu; Mengke Qu; Liuqing Yang; Xun Sun; Tao Gong; Zhirong Zhang; Qing Lin; Ling Zhang

doi:10.1002/ADFM.201870294

Published on Oct 1, 2018in Advanced Functional Materials18.808

· DOI :10.1002/ADFM.201870294

Yu Fu7

Estimated H-index: 7

(Sichuan University), Wei Liu3

Estimated H-index: 3

(Sichuan University)+ 8 AuthorsLing Zhang10

Estimated H-index: 10

(Sichuan University)

Abstract

Cited By1

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Erythrocyte-Membrane-Enveloped Biomineralized Metal-Organic Framework Nanoparticles Enable Intravenous Glucose-Responsive Insulin Delivery.

Apr 23, 2021·ACS Applied Materials & Interfaces9.23

#1Mengyun He (Hunan University)H-Index: 6

#2Pei Yu (Hunan University)

Last. Xia Chu (Hunan University)H-Index: 39

view all 7 authors...

A "closed-loop" insulin delivery system that can mimic the dynamic and glucose-responsive insulin secretion as islet β-cells is desirable for the therapy of type 1 and advanced type 2 diabetes mellitus (T1DM and T2DM). Herein, we introduced a kind of "core-shell"-structured glucose-responsive nanoplatform to achieve intravenous "smart" insulin delivery. A finely controlled one-pot biomimetic mineralization method was utilized to coencapsulate insulin, glucose oxidase (GOx), and catalase (CAT) in...more

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