Insulin Delivery: Erythrocyte‐Membrane‐Camouflaged Nanoplatform for Intravenous Glucose‐Responsive Insulin Delivery (Adv. Funct. Mater. 41/2018)

Published on Oct 1, 2018in Advanced Functional Materials18.808
· DOI :10.1002/ADFM.201870294
Yu Fu7
Estimated H-index: 7
(Sichuan University),
Wei Liu3
Estimated H-index: 3
(Sichuan University)
+ 8 AuthorsLing Zhang10
Estimated H-index: 10
(Sichuan University)
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#1Mengyun He (Hunan University)H-Index: 6
#2Pei Yu (Hunan University)
Last. Xia Chu (Hunan University)H-Index: 39
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A "closed-loop" insulin delivery system that can mimic the dynamic and glucose-responsive insulin secretion as islet β-cells is desirable for the therapy of type 1 and advanced type 2 diabetes mellitus (T1DM and T2DM). Herein, we introduced a kind of "core-shell"-structured glucose-responsive nanoplatform to achieve intravenous "smart" insulin delivery. A finely controlled one-pot biomimetic mineralization method was utilized to coencapsulate insulin, glucose oxidase (GOx), and catalase (CAT) in...
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