Licochalcone A attenuates acne symptoms mediated by suppression of NLRP3 inflammasome

Volume: 32, Issue: 12, Pages: 2551 - 2559
Published: Oct 3, 2018
Abstract
Activation of the NACHT, LRR and PYD domains‐containing protein 3 (NLRP3) inflammasome by Propionibacterium acnes ( P . acnes ) is critical for inducing inflammation and aggravating the development of acne lesions. We searched for available small‐molecule inhibitors of the NLRP3 inflammasome that could be topically administered for the treatment of acne. We found that licochalcone A, a chalconoid isolated from the root of Glycyrrhiza inflate ,...
Paper Details
Title
Licochalcone A attenuates acne symptoms mediated by suppression of NLRP3 inflammasome
Published Date
Oct 3, 2018
Volume
32
Issue
12
Pages
2551 - 2559
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.