The Role of Type 1 Conventional Dendritic Cells in Cancer Immunity
Abstract
Dendritic cells (DCs) are key orchestrators of immune responses. A specific DC subset, conventional type 1 DCs (cDC1s), has been recently associated with human cancer patient survival and, in preclinical models, is critical for the spontaneous rejection of immunogenic cancers and for the success of T cell-based immunotherapies. The unique role of cDC1 reflects the ability to initiate de novo T cell responses after migrating to tumor-draining...
Paper Details
Title
The Role of Type 1 Conventional Dendritic Cells in Cancer Immunity
Published Date
Nov 1, 2018
Journal
Volume
4
Issue
11
Pages
784 - 792
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