Overexpression of miR‑574‑3p suppresses proliferation and induces apoptosis of chronic myeloid leukemia cells via targeting IL6/JAK/STAT3 pathway

The present study aimed to elucidate the potential roles and regulatory mechanism of microRNA (miR)‑574‑3p in the development of chronic myeloid leukemia (CML). The expression of miR‑574‑3p in peripheral blood obtained from patients with CML was examined. Subsequently, miR‑574‑3p was overexpressed and suppressed in CML K562 cells to further investigate the effects of miR‑574‑3p on cell proliferation, and apoptosis. Furthermore, a luciferase...