Original paper
Dependence of Heterogeneous Nucleation on Hydrogen Bonding Lifetime and Complementarity
Abstract
The crystallization of seven active pharmaceutical ingredients (APIs) (acetaminophen (AAP), carbamazepine (CBMZ), caffeine (CAF), phenylbutazone (PBZ), risperidone (RIS), clozapine base (CPB), and fenofibrate (FF)) was studied in the absence and presence of microcrystalline cellulose (MCC) which acted as a heterosurface. Two of the active pharmaceutical ingredients (APIs), namely, AAP and CBMZ, possess hydrogen bond donor (HBD) and hydrogen bond...
Paper Details
Title
Dependence of Heterogeneous Nucleation on Hydrogen Bonding Lifetime and Complementarity
Published Date
Sep 19, 2018
Journal
Volume
18
Issue
11
Pages
7158 - 7172
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Notes
History