Porphyrinoid biohybrid materials as an emerging toolbox for biomedical light management.

Published on Oct 1, 2018in Chemical Society Reviews42.846
· DOI :10.1039/C7CS00554G
Verónica Almeida-Marrero2
Estimated H-index: 2
(UAM: Autonomous University of Madrid),
Eveline van de Winckel5
Estimated H-index: 5
(UAM: Autonomous University of Madrid)
+ 2 AuthorsAndrés de la Escosura23
Estimated H-index: 23
(UAM: Autonomous University of Madrid)
Sources
Abstract
The development of photoactive and biocompatible nanomaterials is a current major challenge of materials science and nanotechnology, as they will contribute to promoting current and future biomedical applications. A growing strategy in this direction consists of using biologically inspired hybrid materials to maintain or even enhance the optical properties of chromophores and fluorophores in biological media. Within this area, porphyrinoids constitute the most important family of organic photosensitizers. The following extensive review will cover their incorporation into different kinds of photosensitizing biohybrid materials, as a fundamental research effort toward the management of light for biomedical use, including technologies such as photochemical internalization (PCI), photoimmunotherapy (PIT), and theranostic combinations of fluorescence imaging and photodynamic therapy (PDT) or photodynamic inactivation (PDI) of microorganisms.
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