Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis
Abstract
There are limited treatments for progressive multiple sclerosis. Ibudilast inhibits several cyclic nucleotide phosphodiesterases, macrophage migration inhibitory factor, and toll-like receptor 4 and can cross the blood–brain barrier, with potential salutary effects in progressive multiple...
Paper Details
Title
Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis
Published Date
Aug 30, 2018
Volume
379
Issue
9
Pages
846 - 855
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