Asleep blood pressure: significant prognostic marker of vascular risk and therapeutic target for prevention

Sleep-time blood pressure (BP) is a stronger risk factor for cardiovascular disease (CVD) events than awake and 24 h BP means, but the potential role of asleep BP as therapeutic target for diminishing CVD risk is uncertain. We investigated whether CVD risk reduction is most associated with progressive decrease of either office or ambulatory awake or asleep BP mean.We prospectively evaluated 18 078 individuals with baseline ambulatory BP ranging...