This paper develops a robust adaptive neural network (NN) tracking control scheme for a class of strict-feedback nonlinear systems with unknown nonlinearities and unknown external disturbances under input saturation. The radial basis function NNs with minimal learning parameter (MLP) are employed to online approximate the uncertain system dynamics. The adaptive laws are designed to online update the upper bound of the norm of ideal NN weight vectors , and the sum of the bounds of NN approximation errors and external disturbances, respectively. An auxiliary dynamic system is constructed to generate the augmented error signals which are used to modify the adaptive laws for preventing the destructive action due to the input saturation. Moreover, the command filtering backstepping control method is utilized to overcome the shortcoming of dynamic surface control method, the tracking-differentiator-based control method, etc. Our proposed scheme is qualified for simultaneously dealing with the input saturation effect , the heavy computational burden and the “explosion of complexity” problems. Theoretical analysis illuminates that our scheme ensures the boundedness of all signals in the closed-loop systems. Simulation results on two examples verify the effectiveness of our developed control scheme.