Original paper
Dynamic m6A methylation facilitates mRNA triaging to stress granules
Abstract
Reversible post-transcriptional modifications on messenger RNA emerge as prevalent phenomena in RNA metabolism. The most abundant among them is N6-methyladenosine (m6A) which is pivotal for RNA metabolism and function; its role in stress response remains elusive. We have discovered that in response to oxidative stress, transcripts are additionally m6A modified in their 5' vicinity. Distinct from that of the translationally active mRNAs, this...
Paper Details
Title
Dynamic m6A methylation facilitates mRNA triaging to stress granules
Published Date
Jul 3, 2018
Journal
Volume
1
Issue
4
Pages
e201800113 - e201800113
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Notes
History