Review paper
Proteomic study of endothelial dysfunction induced by AGEs and its possible role in diabetic cardiovascular complications
Abstract
Endothelial dysfunction is one of the primary steps in the development of diabetes associated cardiovascular diseases. Hyperglycemic condition in diabetes promotes accumulation of advanced glycation end products (AGEs) in the plasma, that interact with the receptor for AGEs (RAGE) present on the endothelial cells and negatively affect their function. Using Human umbilical vascular endothelial cells (HUVECs) in culture, the effect of glycated...
Paper Details
Title
Proteomic study of endothelial dysfunction induced by AGEs and its possible role in diabetic cardiovascular complications
Published Date
Sep 1, 2018
Journal
Volume
187
Pages
69 - 79
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