Gene

Engineering

Ecology

Biology

Biochemistry

Vector (molecular biology)

Tick

Tick infestation

Transmission (telecommunications)

Zoology

Host (biology)

Recombinant DNA

Tick-borne disease

Electrical engineering

Veterinary Sciences

Ticks transmit the most diverse array of infectious agents of any arthropod vector. Both ticks and the microbes they transmit are recognized as significant threats to human and veterinary public health. This article examines the potential impacts of climate change on the distribution of ticks and the infections they transmit; the emergence of novel tick-borne pathogens, increasing geographic range and incidence of tick-borne infections; and advances in the characterization of tick saliva mediated modulation of host defenses and the implications of those interactions for transmission, establishment, and control of tick infestation and tick-borne infectious agents.

Ticks and Tick-Borne Infections: Complex Ecology, Agents, and Host Interactions