Internal medicine

Radiology

Retrospective cohort study

Wedge resection

Surgical oncology

Margin (machine learning)

Biology

Cancer

Machine learning

Resection

Surgery

Oncology

Stage (stratigraphy)

Paleontology

Lung

Lung cancer

Surgical margin

Metastasis

Pneumonectomy

Resection margin

Computer science

Medicine

Surgery Today

Stage I non-small cell lung cancer (NSCLC) is a localized disease without metastasis; therefore, it can be treated effectively with local therapies. Pulmonary resection is the most frequent treatment, performed as pulmonary wedge resection, segmentectomy, lobectomy, or pneumonectomy. Some retrospective clinical studies of pulmonary wedge resection suggest that its outcome may be inferior to that of anatomical pulmonary resection, whereas other recent studies, which assess surgical margin status, leveled acceptable outcomes. Since the outcome of pulmonary wedge resection for lung cancer may depend on tumor size, distance from the surgical margin to the tumor, tumor size/margin distance ratio, and margin cytology results, a prospective study assessing these parameters is ongoing. This will allow us to identify the clinical implications of these factors and predict which patients are likely to have a good outcome.

Validating margin status in lung wedge resection for clinical stage I non-small cell lung cancer