Physics

Neuroscience

Receptor

Dendritic spine

Visual cortex

Psychotherapist

Biology

Hippocampal formation

Receptive field

Psychology

Long-term potentiation

Neuron

Stimulus (psychology)

Synaptic plasticity

Neuroplasticity

Optogenetics

Biochemistry

Plasticity

Thermodynamics

Science

Rebalancing strength between synapses Activation of a neuronal pathway is often associated with inhibition of surrounding pathways. How locally coordinated synaptic plasticity occurs in vivo is not known, nor is its role in shaping neuronal responses. El-Boustani et al. paired optogenetic stimulation of single neurons with a visual input and were able to shift the neuron's receptive field toward the target location. Spines that expressed structural long-term potentiation had receptive fields overlapping the target stimulus but were surrounded by spines that expressed receptive fields away from the target. Science , this issue p. 1349

Locally coordinated synaptic plasticity of visual cortex neurons in vivo