Abstract Glycerol citrate polyester based on the condensation of glycerol and citric acid has a great potential in biomedical applications owing to biocompatible monomers and biodegradation properties. However, the applications of glycerol citrate polyester are impaired by its poor mechanical properties and high acidity caused by citric acid produced in the degradation process. In this work, a new kind of nanocomposite has been developed using ultralong hydroxyapatite (HAP) nanowires as the “skeleton”, and strongly bound glycerol citrate polyester as the “muscle”. The ultralong HAP nanowires interweave with each other to form a three-dimensional nanoporous network, and glycerol citrate polyester is homogeneously distributed in the nanoporous network. Owing to the reinforcement of ultralong HAP nanowires, the mechanical properties of the as-prepared nanocomposite are significantly improved compared with the pure glycerol citrate polyester, and the tensile strength even reaches to the level of human cortical bones. Furthermore, the acidity of the aqueous solution after degradation is neutralized by the reaction between citric acid and ultralong HAP nanowires, and the pH value can be stabilized. The as-prepared nanocomposite can solve some problems of the pure glycerol citrate polyester, and shows promising applications in the biomedical field.
#1Tuan-Wei Sun(CAS: Chinese Academy of Sciences)H-Index: 20
#2Ying-Jie Zhu(CAS: Chinese Academy of Sciences)H-Index: 81
Last. Feng Chen(CAS: Chinese Academy of Sciences)H-Index: 55
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The highly flexible multifunctional biopaper comprising ultralong hydroxyapatite nanowires and chitosan (UHANWs/CS) with high weight fractions of ultralong hydroxyapatite nanowires (UHANWs) up to 100 wt.% is reported herein. The as-prepared UHANWs/CS composite biopaper has high flexibility and superior mechanical properties even when the weight fraction of UHANWs is as high as 90 wt.%. In contrast, the control samples consisting of hydroxyapatite nanorods and chitosan (HANRs/CS) with weight frac...
#1Tuan-Wei Sun(CAS: Chinese Academy of Sciences)H-Index: 20
#2Ying-Jie Zhu(CAS: Chinese Academy of Sciences)H-Index: 81
Last. Yong-Gang Zhang(CAS: Chinese Academy of Sciences)H-Index: 14
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Abstract Highly flexible hydroxyapatite/collagen (HAP/Col) composite membranes are regarded to be significant for guided bone regeneration application owing to their similar chemical composition to that of natural bone, excellent bioactivity and good osteoconductivity. However, the mechanical strength of the HAP/Col composite membranes is usually weak, which leads to difficult surgical operations and low mechanical stability during the bone healing process. Herein, highly flexible ultralong hydr...
#1Feng Chen(CAS: Chinese Academy of Sciences)H-Index: 55
#2Ying-Jie Zhu(CAS: Chinese Academy of Sciences)H-Index: 81
Practical applications of nanostructured materials have been largely limited by the difficulties in controllable and scaled-up synthesis, large-sized highly ordered self-assembly, and macroscopic processing of nanostructures. Hydroxyapatite (HAP), the major inorganic component of human bone and tooth, is an important biomaterial with high biocompatibility, bioactivity, and high thermal stability. Large-sized highly ordered HAP nanostructures are of great significance for applications in various ...
#1Ying-Ying Jiang(CAS: Chinese Academy of Sciences)H-Index: 14
#2Ying-Jie Zhu(CAS: Chinese Academy of Sciences)H-Index: 81
Last. Jin Wu(CAS: Chinese Academy of Sciences)H-Index: 59
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Abstract Hydroxyapatite (Ca 10 (OH) 2 (PO 4 ) 6 , HAP), as the major inorganic component of bones and teeth in vertebrates, is a very important biomaterial with high biocompatibility, nontoxicity and high thermal stability, thus, it has wide applications in various biomedical fields. Among various morphologies of HAP, HAP nanowires are very promising for various applications; however, the synthesis of ultralong HAP nanowires with lengths larger than 100 μm is highly challengeable and has been ra...
#2Valeria Chiono(Polytechnic University of Turin)H-Index: 31
Last. Paul V. Hatton(University of Sheffield)H-Index: 32
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Poly(lactic-co-glycolic) acid (PLGA) has attracted considerable interest as a base material for biomedical applications due to its: (i) biocompatibility; (ii) tailored biodegradation rate (depending on the molecular weight and copolymer ratio); (iii) approval for clinical use in humans by the U.S. Food and Drug Administration (FDA); (iv) potential to modify surface properties to provide better interaction with biological materials; and (v) suitability for export to countries and cultures where i...
#1Bing-Qiang Lu(CAS: Chinese Academy of Sciences)H-Index: 22
#2Ying-Jie Zhu(CAS: Chinese Academy of Sciences)H-Index: 81
Last. Feng Chen(CAS: Chinese Academy of Sciences)H-Index: 55
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A highly flexible and nonflammable inorganic hydroxyapatite (HAP) paper made from HAP ultralong nanowires is reported. The paper can be used for printing and writing and is promising for the permanent and safe storage of information, such as archives and important documents. The HAP paper is also an excellent and recyclable adsorbent for organic pollutants.
#1Brent Tisserat(USDA: United States Department of Agriculture)H-Index: 16
#2Rogers Harry O'kuru(USDA: United States Department of Agriculture)H-Index: 1
Last. Ronald A. Holser(USDA: United States Department of Agriculture)H-Index: 16
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The influence of various heating methods without catalysis to prepare polyesters from citric acid : glycerol blends were studied. In the presence of short-term microwave treatments, i.e., 60 s at 1200 W, blends of glycerol and citric acid invariably formed solid amorphous polyesters. Fourier transform infrared spectroscopy showed that citric acid and glycerol blends can form highly stable polymers composed of ester bonds. The glycerol citrate polyester polymers exhibited the least degradation in...
Last. Kangde Yao(TJU: Tianjin University)H-Index: 60
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Abstract Nano-hydroxyapatite/chitosan–pectin (nHCP) composite was prepared via mineralization of a chitosan–pectin network. Then nHCP/chitosan–gelatin (nHCP/CG) scaffolds were prepared via the blending of nHCP and chitosan–gelatin solution. Results suggested that nHCP/CG scaffolds have appropriate porosity, water absorption ability and degradation behaviors. nHCP can be fused into the pore wall of nHCP/CG scaffold via chemical crosslinking interactions, which avoids the agglomeration and migrati...
We describe a novel approach to process bioceramic microparticles and poly(diol citrates) into bioceramic–elastomer composites for potential use in orthopedic surgery. The composite consists of the biodegradable elastomer poly(1,8-octanediol-citrate) (POC) and the bioceramic hydroxyapatite (HA). The objective of this work was to characterize POC–HA composites and assess the feasibility of fabricating tissue fixation devices using machining and molding techniques. The mechanical properties of POC...
Last. Sudin Izman(UTM: Universiti Teknologi Malaysia)H-Index: 20
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In recent years, there has been a rising awareness on non-renewable resources and environmental sustainability. This has bolstered researchers’ efforts to design more environmentally friendly materials with a focus on sustainability, and transitioning from the use of synthetic to natural materials. Natural fibers can potentially be an alternative to synthetic fibers as reinforcement materials, used in various industries. However, a comprehensive investigation is necessary in order to understand ...
Calcium phosphate cements (CPCs) belong to one of the most prominent biomaterials used for filling and regeneration of hard tissues, however poor mechanical and biological properties limit their widespread use in some clinical applications. To solve these problems, a biodegradable glycerol-citrate (G-CA) polyester was synthesized and coated on tricalcium phosphate cement (TCP) powders in amounts up to 10 wt% of the G-CA content using a simple solution infiltration technique in ethanol solution. ...
Poly(glycerol citrate) is a biodegradable aliphatic polyester made of citric acid and glycerol. Because of the high functionality of the reactants, citric acid—4 and glycerol—3, there are many poss...
Abstract Synthetic textiles make a great contribution as the apparel, industrial and technical textile goods, though most of them are inherently flammable. Thus, the fire retardant treatment of synthetic textile materials always puts a huge significance to deal with; meanwhile the art of flame retardant application is taking a new shape globally considering the modification of the textile surfaces as well as the structure of applied flame retardant compounds. Thus, this review depicts the fire r...
#1Xiaodong Liu(Huada: Beijing University of Chemical Technology)H-Index: 11
#2Xiaowei Meng(Huada: Beijing University of Chemical Technology)H-Index: 2
Last. Sheng Zhang(Huada: Beijing University of Chemical Technology)H-Index: 26
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Layer by layer (LBL) assembly technique was used to deposit multilayer coating containing phosphorus-nitrogen onto the surface of fibers to improve the flame retardancy of polyester-cotton (PET-COT) blended fabric. Ellipsometer results confirmed that polyallylamine hydrochloride (PAH), melamine (MEL), and ammonium polyphosphate (APP) grew linearly on silicon wafer during the LbL process. The LOI value of coated PET-COT fabric was increased from 20.8% of pristine fabric to 28.4% by the presence o...
Last. Monika Bzowska(Jagiellonian University)H-Index: 15
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Background The functionalization of a nanoparticle surface with PEG (polyethylene glycol) is an approach most often used for extending nanomaterial circulation time, enhancing its delivery and retention in the target tissues, and decreasing systemic toxicity of nanocarriers and their cargos. However, because PEGylated nanomedicines were reported to induce immune response including production of anti-PEG antibodies, activation of the complement system as well as hypersensitivity reactions, hydrop...
Abstract Bionanocomposites from low cost and non-scarce resource tapioca starch (TS)-based film were synthesized for food packaging applications. Two types of crosslinkers, namely Citrus aurantifolia , also known as lime juice (LJ), and a commercialized citric acid (CA), were used one at a time with glycerol via solvent casting for comparison purposes. Varying amounts of nanocellulose (NC) extracted from oil palm empty fruit bunches (OPEFB) were added as the reinforcing filler via acid hydrolysi...
