The Diverse Genomic Landscape of Clinically Low-risk Prostate Cancer

Among men with clinically low-risk prostate cancer, we have previously documented heterogeneity in terms of clinical characteristics and genomic risk scores. To further study the underlying tumor biology of this patient population, by interrogating broader patterns of gene expression among men with clinically low-risk tumors. Prostate biopsies from 427 patients considered potentially suitable for active surveillance underwent central pathology...