Targeting oncogenic Myc as a strategy for cancer treatment
Abstract
The MYC family oncogene is deregulated in >50% of human cancers, and this deregulation is frequently associated with poor prognosis and unfavorable patient survival. Myc has a central role in almost every aspect of the oncogenic process, orchestrating proliferation, apoptosis, differentiation, and metabolism. Although Myc inhibition would be a powerful approach for the treatment of many types of cancers, direct targeting of Myc has been a...
Paper Details
Title
Targeting oncogenic Myc as a strategy for cancer treatment
Published Date
Feb 23, 2018
Volume
3
Issue
1
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