Ultrahigh-throughput droplet microfluidic device for single-cell miRNA detection with isothermal amplification

Volume: 18, Issue: 13, Pages: 1914 - 1920
Published: Jan 1, 2018
Abstract
Analysis of microRNA (miRNA), a pivotal primary regulator of fundamental cellular processes, at the single-cell level is essential to elucidate regulated gene expression precisely. Most single-cell gene sequencing methods use the polymerase chain reaction (PCR) to increase the concentration of the target gene for detection, thus requiring a barcoding process for cell identification and creating a challenge for real-time, large-scale screening of...
Paper Details
Title
Ultrahigh-throughput droplet microfluidic device for single-cell miRNA detection with isothermal amplification
Published Date
Jan 1, 2018
Volume
18
Issue
13
Pages
1914 - 1920
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