Pediatrics

Epilepsy

Psychiatry

Cannabis

Cannabidiol

Lennox–Gastaut syndrome

Medicine

New England Journal of Medicine

Cannabidiol has been used for treatment-resistant seizures in patients with severe early-onset epilepsy. We investigated the efficacy and safety of cannabidiol added to a regimen of conventional antiepileptic medication to treat drop seizures in patients with the Lennox–Gastaut syndrome, a severe developmental epileptic encephalopathy.

Effect of Cannabidiol on Drop Seizures in the Lennox–Gastaut Syndrome