Review paper
The personal and clinical utility of polygenic risk scores
Abstract
Initial expectations for genome-wide association studies were high, as such studies promised to rapidly transform personalized medicine with individualized disease risk predictions, prevention strategies and treatments. Early findings, however, revealed a more complex genetic architecture than was anticipated for most common diseases - complexity that seemed to limit the immediate utility of these findings. As a result, the practice of utilizing...
Paper Details
Title
The personal and clinical utility of polygenic risk scores
Published Date
May 22, 2018
Journal
Volume
19
Issue
9
Pages
581 - 590
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