Immobilization of bovine serum albumin via mussel-inspired polydopamine coating on electrospun polyethersulfone (PES) fiber mat for effective bilirubin adsorption

Hyperbilirubinemia could be treated effectively by hemoperfusion. Electrospinning fiber mat had been reported to be applied in the hemoperfusion field owing to its higher surface area. BSA, as one of the natural carrier proteins for bilirubin, can not only selectively adsorb bilirubin but also improve the hemocompatibility of biomaterials. In this work, functionalized polyethersulfone (PES) electrospun fiber mat was prepared by immobilizing BSA...