Overcoming Ovarian Cancer Drug Resistance with a Cold Responsive Nanomaterial
Abstract
Drug resistance due to overexpression of membrane transporters in cancer cells and the existence of cancer stem cells (CSCs) is a major hurdle to effective and safe cancer chemotherapy. Nanoparticles have been explored to overcome cancer drug resistance. However, drug slowly released from nanoparticles can still be efficiently pumped out of drug-resistant cells. Here, a hybrid nanoparticle of phospholipid and polymers is developed to achieve...
Paper Details
Title
Overcoming Ovarian Cancer Drug Resistance with a Cold Responsive Nanomaterial
Published Date
Apr 17, 2018
Journal
Volume
4
Issue
5
Pages
567 - 581
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