Acid-Resistant Mesoporous Metal–Organic Framework toward Oral Insulin Delivery: Protein Encapsulation, Protection, and Release

Volume: 140, Issue: 17, Pages: 5678 - 5681
Published: Apr 11, 2018
Abstract
Diabetes affects millions of people worldwide and the number of diagnoses continues to climb annually. Though several effective medications and therapeutic methods have been developed to treat type 1 (T1DM) and type 2 (T2DM) diabetes mellitus, direct insulin injection remains the only effective treatment for insulin resistant (IR) diabetes patients. Here, we immobilize insulin in a crystalline mesoporous metal–organic framework (MOF), NU-1000,...
Paper Details
Title
Acid-Resistant Mesoporous Metal–Organic Framework toward Oral Insulin Delivery: Protein Encapsulation, Protection, and Release
Published Date
Apr 11, 2018
Volume
140
Issue
17
Pages
5678 - 5681
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