Oleic acid enhances keratinocytes differentiation via the upregulation of miR‐203 in human epidermal keratinocytes

Summary Background Oleic acid ( OA ) is an unsaturated free fatty acid ( FFA ) constituent of sebum. FFA s modulate keratinocyte differentiation. In this study, we determined whether OA affects keratinocyte differentiation in neonatal human epidermal keratinocytes ( HEK n). Methods HEK n was grown in EpiLife medium. The cells were treated with various concentrations of OA . The expression levels of keratin 10 and involucrin were determined using...