Gene

Engineering

Biology

Arbovirus

Virology

Yellow fever

Telecommunications

Biochemistry

Computer science

Vector (molecular biology)

Geography

Internal medicine

Epidemiology

Medicine

Transmission (telecommunications)

Virus

Recombinant DNA

Arbovirus Infections

Electrical engineering

Science

Arbovirus risk in Brazil Despite the existence of an effective vaccine for yellow fever, there are still almost 80,000 fatalities from this infection each year. Since 2016, there has been a resurgence of cases in Africa and South America—and this at a time when the vaccine is in short supply. The worry is that yellow fever will spread from the forests to the cities, because its vector, Aedes spp. mosquitoes, are globally ubiquitous. Faria et al. integrate genomic, epidemiological, and case distribution data from Brazil to estimate patterns of geographic spread, the risks of virus exposure, and the contributions of rural versus urban transmission (see the Perspective by Barrett). Currently, the yellow fever epidemic in Brazil seems to be driven by infections acquired while visiting forested areas and indicates spillover from susceptible wild primates. Science , this issue p. 894 ; see also p. 847

Genomic and epidemiological monitoring of yellow fever virus transmission potential