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Original paper

Kourami: graph-guided assembly for novel human leukocyte antigen allele discovery

Volume: 19, Issue: 1
Published: Feb 7, 2018
Abstract
Accurate typing of human leukocyte antigen (HLA) is important because HLA genes play important roles in immune responses and disease genesis. Previously available computational methods are database-matching approaches and their outputs are inherently limited by the completeness of already known types, making them unsuitable for discovery of novel alleles. We have developed a graph-guided assembly technique for classical HLA genes, which can...
Paper Details
Title
Kourami: graph-guided assembly for novel human leukocyte antigen allele discovery
Published Date
Feb 7, 2018
Volume
19
Issue
1
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