Targeting cytokines to treat asthma and chronic obstructive pulmonary disease
Abstract
Cytokines play a key role in orchestrating and perpetuating the chronic airway inflammation in asthma and chronic obstructive pulmonary disease (COPD), making them attractive targets for treating these disorders. Asthma and some cases of COPD are mainly driven by type 2 immune responses, which comprise increased airway eosinophils, T helper 2 (TH2) cells and group 2 innate lymphoid cells (ILC2s) and the secretion of IL-4, IL-5 and IL-13....
Paper Details
Title
Targeting cytokines to treat asthma and chronic obstructive pulmonary disease
Published Date
Apr 6, 2018
Journal
Volume
18
Issue
7
Pages
454 - 466
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Notes
History