Air pollution

Demography

Ecology

Biology

Statistics

Pollution

Cohort study

Environmental health

Regression analysis

Rate ratio

Organic chemistry

Mathematics

Population

Internal medicine

Sociology

Geometry

Air pollutants

Epidemiology

Medicine

Chemistry

Poisson regression

Incidence (geometry)

Environment International

The association between air pollution and rhinitis is not well established. The aim of this longitudinal analysis was to study the association between modeled air pollution at the subjects' home addresses and self-reported incidence of rhinitis. We used data from 1533 adults from two multicentre cohorts' studies (EGEA and ECRHS). Rhinitis incidence was defined as reporting rhinitis at the second follow-up (2011 to 2013) but not at the first follow-up (2000 to 2007). Annual exposure to NO2, PM10 and PM2.5 at the participants' home addresses was estimated using land-use regression models developed by the ESCAPE project for the 2009–2010 period. Incidence rate ratios (IRR) were computed using Poisson regression. Pooled analysis, analyses by city and meta-regression testing for heterogeneity were carried out. No association between long-term air pollution exposure and incidence of rhinitis was found (adjusted IRR (aIRR) for an increase of 10 μg·m−3 of NO2: 1.00 [0.91–1.09], for an increase of 5 μg·m−3 of PM2.5: 0.88 [0.73–1.04]). Similar results were found in the two-pollutant model (aIRR for an increase of 10 μg·m−3 of NO2: 1.01 [0.87–1.17], for an increase of 5 μg·m−3 of PM2.5: 0.87 [0.68–1.08]). Results differed depending on the city, but no regional pattern emerged for any of the pollutants. This study did not find any consistent evidence of an association between long-term air pollution and incident rhinitis.

Association between air pollution and rhinitis incidence in two European cohorts