Abstract null null Background null In modern urban environments children have a high incidence of inflammatory disorders, including allergies, asthma, and type 1 diabetes. The underlying cause of these disorders, according to the biodiversity hypothesis, is an imbalance in immune regulation caused by a weak interaction with environmental microbes. In this 2-year study, we analyzed bacterial community shifts in the soil surface in day-care centers and commensal bacteria inhabiting the mouth, skin...
#1Limei Shi(HUST: Huazhong University of Science and Technology)
#2Yu Yuan(HUST: Huazhong University of Science and Technology)H-Index: 8
Last. Lue Zhou(HUST: Huazhong University of Science and Technology)H-Index: 7
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BACKGROUND Exposure to metals/metalloids from both the natural environment and anthropogenic sources have a complex influence on human health. However, relatively few studies have explored the relations of exposure to multiple metals/metalloids with mortality. Therefore, this prospective study aims to examine the relations of multiple metal/metalloids exposures with all-cause and cardiovascular disease (CVD) mortality. METHODS A total of 6155 participants within the Dongfeng-Tongji (DF-TJ) cohor...
Last. Daniel Zalko(University of Toulouse)H-Index: 36
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Abstract null null Background null Endocrine disrupting chemicals (EDCs) contribute to the etiology of metabolic disorders such as obesity, insulin resistance and hepatic dysfunction. Concern is growing about the consequences of perinatal EDC exposure on disease predisposition later in life. Metabolomics are promising approaches for studying long-term consequences of early life EDC exposure. These approaches allow for the identification and characterization of biomarkers of direct or ancestral e...
Abstract Background Patients at high risk of severe forms of COVID-19 frequently suffer from chronic diseases, but other risk factors may also play a role. Environmental stressors, such as endocrine disrupting chemicals (EDCs), can contribute to certain chronic diseases and might aggravate the course of COVID-19. Objectives To explore putative links between EDCs and COVID-19 severity, an integrative systems biology approach was constructed and applied. Methods As a first step, relevant data sets...
#1Chaochen Ma(National Institute for Environmental Studies)H-Index: 3
#2Miyuki Iwai-Shimada(National Institute for Environmental Studies)H-Index: 13
Last. Shin Yamazaki(National Institute for Environmental Studies)H-Index: 26
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BACKGROUND Prenatal cadmium exposure has been associated with adverse neurodevelopmental outcomes. However, previous findings are contradictory, and little is known about the potential modifiers of the cadmium-related neurodevelopmental risk. We investigated the associations between prenatal cadmium exposure and neurodevelopment in 2-year-old children and examined the influence of mother/child characteristics. METHODS We recruited 3545 mother-child pairs from the Japan Environment and Children's...
Last. Jiuhui Qu(CAS: Chinese Academy of Sciences)H-Index: 100
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Abstract null null The ecological stress of microplastic contamination to ecosystem functioning and biota raises concerns worldwide, but the impacts of microplastics on wetland ecosystems (e.g., plants, microbes, and soil) have not been fully elucidated. In this study, we used a controlled pot experiment to determine the effects of different types (PS, PVC, PP and PE) of microplastics on the growth performance of wetland plants, soil chemical properties, enzyme systems and microbial communities....
Abstract Industrial chemicals such as persistent organic pollutants (POPs) have been associated with reduced fertility in women, including longer time-to-pregnancy (TTP), higher odds for infertility, and earlier reproductive senescence. Fertility is highly dependent on the ovarian reserve, which is composed of a prenatally determined stock of non-growing follicles. The quantity and quality of the follicles decline with age, thereby eventually leading to menopause. In the clinical setting, assess...
#1Ruiwen Hu(SYSU: Sun Yat-sen University)H-Index: 1
#1Ruiwen Hu(SYSU: Sun Yat-sen University)H-Index: 1
Last. Cheng Wang(SYSU: Sun Yat-sen University)H-Index: 12
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Abstract The extensive use of phthalic acid esters (PAEs) has led to their widespread distribution across various environments. As PAEs pose significant threats to human health, it is urgent to develop efficient strategies to eliminate them from environments. Bacteria-driven PAE biodegradation has been considered as an inexpensive yet effective strategy to restore the contaminated environments. Despite great advances in bacterial culturing and sequencing, the inherent complexity of indigenous mi...
#1Frank Pega(WHO: World Health Organization)H-Index: 17
#2Bálint Náfrádi(ILO: International Labour Organization)H-Index: 1
Last. Tracey J. Woodruff(UCSF: University of California, San Francisco)H-Index: 68
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Abstract Background World Health Organization (WHO) and International Labour Organization (ILO) systematic reviews reported sufficient evidence for higher risks of ischemic heart disease and stroke amongst people working long hours (≥55 hours/week), compared with people working standard hours (35–40 hours/week). This article presents WHO/ILO Joint Estimates of global, regional, and national exposure to long working hours, for 194 countries, and the attributable burdens of ischemic heart disease ...
#2Xiaoqiang Cao(SDUST: Shandong University of Science and Technology)
Last. Weiling Sun(PKU: Peking University)H-Index: 29
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Although nanoplastics/microplastics (NPs/MPs) may interact with co-contaminants (e.g. antibiotics) in aquatic systems, little is known about their combined toxicity. Here, we compared the individual toxicity of NPs/MPs or ciprofloxacin (CIP, a very commonly detected antibiotic) and their combined toxicity toward a unicellular cyanobacterium Synechocystis sp. in terms of the cellular responses and metabolomic analysis. We found that CIP exhibited an antagonistic effect with NPs/MPs due to its ads...