The Multifunctional Protein BAG3

Volume: 3, Issue: 1, Pages: 122 - 131
Published: Feb 1, 2018
Abstract
The B-cell lymphoma 2–associated anthanogene (BAG3) protein is expressed most prominently in the heart, the skeletal muscle, and in many forms of cancer. In the heart, it serves as a co-chaperone with heat shock proteins in facilitating autophagy; binds to B-cell lymphoma 2, resulting in inhibition of apoptosis; attaches actin to the Z disk, providing structural support for the sarcomere; and links the α-adrenergic receptor with the L-type Ca2+...
Paper Details
Title
The Multifunctional Protein BAG3
Published Date
Feb 1, 2018
Volume
3
Issue
1
Pages
122 - 131
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