Review paper
DNA methylation dynamics of genomic imprinting in mouse development†
Abstract
DNA methylation is an essential epigenetic mark crucial for normal mammalian development. This modification controls the expression of a unique class of genes, designated as imprinted, which are expressed monoallelically and in a parent-of-origin-specific manner. Proper parental allele-specific DNA methylation at imprinting control regions (ICRs) is necessary for appropriate imprinting. Processes that deregulate DNA methylation of imprinted loci...
Paper Details
Title
DNA methylation dynamics of genomic imprinting in mouse development†
Published Date
Feb 15, 2018
Journal
Volume
99
Issue
1
Pages
252 - 262
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Notes
History