Original paper
Low shear stress upregulates the expression of fractalkine through the activation of mitogen-activated protein kinases in endothelial cells
Abstract
: Fractalkine (FKN) is a cytokine which plays an important role in atherosclerosis and other inflammatory diseases. Studies have shown that FKN induces integrin-independent leukocyte adhesion to primary endothelial cells under physiological flow conditions. Further, increased expression of FKN has been demonstrated in atherosclerotic lesions induced by low shear stress. However, the signal transduction mechanisms involved in low shear...
Paper Details
Title
Low shear stress upregulates the expression of fractalkine through the activation of mitogen-activated protein kinases in endothelial cells
Published Date
Jun 1, 2018
Volume
29
Issue
4
Pages
361 - 368
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Notes
History