Review paper
Extracellular HMGB1 as a therapeutic target in inflammatory diseases
Volume: 22, Issue: 3, Pages: 263 - 277
Published: Feb 15, 2018
Abstract
High-mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that promotes inflammation when released extracellularly after cellular activation, stress, damage or death. HMGB1 operates as one of the most intriguing molecules in inflammatory disorders via recently elucidated signal and molecular transport mechanisms. Treatments based on antagonists specifically targeting extracellular HMGB1 have generated encouraging results in a wide number...
Paper Details
Title
Extracellular HMGB1 as a therapeutic target in inflammatory diseases
Published Date
Feb 15, 2018
Volume
22
Issue
3
Pages
263 - 277
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