Review paper
Genetic variation in sensitivity to estrogens and breast cancer risk
Abstract
Breast cancer risk is intimately intertwined with exposure to estrogens. While more than 160 breast cancer risk loci have been identified in humans, genetic interactions with estrogen exposure remain to be established. Strains of rodents exhibit striking differences in their responses to endogenous ovarian estrogens (primarily 17β-estradiol). Similar genetic variation has been observed for synthetic estrogen agonists (ethinyl estradiol) and...
Paper Details
Title
Genetic variation in sensitivity to estrogens and breast cancer risk
Published Date
Feb 1, 2018
Journal
Volume
29
Issue
1-2
Pages
24 - 37
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