Nuclear chemistry

Deep eutectic solvent

Engineering

Biology

Geotechnical engineering

Chromatography

Sucrose

Solubility

Rutin

Crude drug

Solvent

Botany

Food science

Extraction (chemistry)

Organic chemistry

Alloy

Eutectic system

Antioxidant

Pharmacology

Medicine

Chemistry

Water content

Pharmaceutics

Curcuma

Citric acid

MATEC Web of Conferences

Recently Natural Deep Eutectic Solvents (NADES) show their potential as a promising green solvents at 21 th century for extraction of natural products. Rutin, a poorly water soluble flavonoid, was reported better solubilized in NADES than in water as well as a paclitaxel and ginkgolide B, a completely water-insoluble compound. In case of curcuminoids, phenolic compounds from powder of Curcuma Zeodaria shown better solubilized in acidic type of NADES such malic acid-sucrose-water (MAS-H 2 O = 1:1:11, mole ratio) and citric acid-sucrose-water (CAS-H 2 O = 1:2:15, mole ratio) compare to water and ethanol. Indicating that NADES, a water-based solvent, appropriate for extracting curcuminoids. However, the inherent high viscosity of NADES hamper the process extraction. Lowering the viscosity, water content of NADES is varied, adding a certain amount of water up to 60% of water content. All the varied water content of both CAS-H 2 O and MAS-H 2 O were successfully extracted curcuminoids. Yielded 0.06-0.16 mg curcuminoids/g dry weight. However, 60% of water content of both CAS-H 2 O and MAS-H 2 O gave more or less similar value of curcuminoids to CAS-H 2 O (20% of water) and MAS-H 2 O (30% of water). Curcuminoids is more stable in CAS-H 2 O compare to MAS-H 2 O for 96 h of time duration.

Tailoring Properties of Acidic Types of Natural Deep Eutectics Solvents (NADES): Enhanced Solubility of Curcuminoids from <i>Curcuma zeodaria</i>

Tailoring Properties of Acidic Types of Natural Deep Eutectics Solvents (NADES): Enhanced Solubility of Curcuminoids from Curcuma zeodaria