Original paper
VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis
Abstract
Chronic pain can develop in response to conditions such as inflammatory arthritis. The central mechanisms underlying the development and maintenance of chronic pain in humans are not well elucidated although there is evidence for a role of microglia and astrocytes. However in pre-clinical models of pain, including models of inflammatory arthritis, there is a wealth of evidence indicating roles for pathological glial reactivity within the CNS. In...
Paper Details
Title
VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis
Published Date
Nov 1, 2018
Journal
Volume
74
Pages
49 - 67
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Notes
History