A Hypothalamic Switch for REM and Non-REM Sleep

Neuron16.20
Volume: 97, Issue: 5, Pages: 1168 - 1176.e4
Published: Mar 1, 2018
Abstract
Rapid eye movement (REM) and non-REM (NREM) sleep are controlled by specific neuronal circuits. Here we show that galanin-expressing GABAergic neurons in the dorsomedial hypothalamus (DMH) comprise separate subpopulations with opposing effects on REM versus NREM sleep. Microendoscopic calcium imaging revealed diverse sleep-wake activity of DMH GABAergic neurons, but the galanin-expressing subset falls into two distinct groups, either selectively...
Paper Details
Title
A Hypothalamic Switch for REM and Non-REM Sleep
Published Date
Mar 1, 2018
Journal
Volume
97
Issue
5
Pages
1168 - 1176.e4
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