Hereditary palmoplantar keratodermas. Part II: syndromic palmoplantar keratodermas – Diagnostic algorithm and principles of therapy

Hereditary palmoplantar keratodermas ( PPK s) comprise a large and heterogeneous group of disorders characterized by persistent thickening of the epidermis at palmar and plantar surfaces. Clinical and genetic features of isolated and complex PPK s have been reviewed in part I of this 2‐part review. Here we focus on clinical and molecular classification of syndromic PPK s which are recognized by additional extracutaneous manifestations, in...