BACKGROUND There are currently no published population-based data on prurigo and pruritus epidemiology in Germany. OBJECTIVES We present the prevalence, incidence, and comorbidity frequency of prurigo and pruritus in Germany. METHODS This was a retrospective healthcare research study based on anonymized routine data from the German health insurance company DAK Gesundheit. Evaluations were carried out for 2,006,003 adults who were insured as of 31 December 2010. Prurigo and pruritus diagnoses wer...
BACKGROUND Certolizumab pegol (CZP) is an Fc-free, PEGylated anti-tumor necrosis factor biologic. OBJECTIVES To report three-year outcomes from the CIMPACT (NCT02346240) phase 3, CZP in moderate to severe plaque psoriasis, randomized controlled trial. METHODS Adults were randomized 3:3:3:1 to CZP 200 mg every other week (Q2W), CZP 400 mg Q2W, etanercept biweekly, or placebo. At Week 16, CZP- and etanercept-treated PASI 75 responders were re-randomized to CZP 200 mg Q2W, CZP 400 mg Q4W, CZP 400 m...
Last. Katharina Meier(Humboldt University of Berlin)H-Index: 2
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Pemphigus vulgaris (PV) is a rare and severe autoimmune disorder of skin and mucosa. In PV, the production of autoantibodies against desmosomal proteins of the skin, namely desmoglein (Dsg) 1 and Dsg3 leads to a clinical phenotype characterized by blistering and severe erosions. Several factors including genetic susceptibility, certain drugs, and malignant disorders have been reported to trigger or exacerbate PV1 . Here, we report the first case of a patient, who developed PV following COVID-19 ...