Prediction of Lipophilicity and Pharmacokinetics of Chloroacetamides by Chemometric Approach.
Abstract
In this study, the existence of biological potential of selected N-(substituted phenyl)-2-chloroacetamides was examined none empirically, as was the possibility of applying simple experimental technique in predicting essential properties which affect the biological activity of the compounds. By applying the Lipinski and Ghose's rules, it has been revealed that the examined chloroacetamides fulfill the theoretical requirements for bioactive...
Paper Details
Title
Prediction of Lipophilicity and Pharmacokinetics of Chloroacetamides by Chemometric Approach.
Published Date
Jan 1, 2018
Journal
Volume
17
Issue
1
Pages
100 - 114
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Notes
History