Catalysis

Composite number

Photochemistry

Materials science

Carbon chain

Carbon fibers

Visible spectrum

Medicinal chemistry

Physics

Chloride

Organic chemistry

Oxygen

Reinforced carbon–carbon

Composite material

Acyl chloride

Double bond

Chemistry

Selectivity

Group (periodic table)

Optoelectronics

Acyl group

The Journal of Organic Chemistry

A novel visible-light-mediated ipso-carboacylation of N-(p-methoxyaryl)propiolamides with acyl chloride has been established for the synthesis of diverse 3-acylspiro[4,5]trienones with high selectivity and efficiency. This method represents a new difunctionalization of alkynes through cross coupling of the acyl chloride C-Cl bonds with an ipso-aromatic carbon by simultaneously forming two new carbon-carbon bonds and one carbon-oxygen double bond.

Visible-Light-Mediated Ipso-Carboacylation of Alkynes: Synthesis of 3-Acylspiro[4,5]trienones from N-(p-Methoxyaryl)propiolamides and Acyl Chlorides