Journal of Organic Chemistry
IF
4.33
Papers
89740
Papers 10000
1 page of 1,000 pages (10k results)
Newest
#1Mahendra A. Wagh (National Chemical Laboratory)
#2Rahul Maity (IISc: Indian Institute of Science)H-Index: 7
Last. Gangadhar J. Sanjayan (National Chemical Laboratory)
view all 7 authors...
This note reports the synthesis and peptide formation of a novel triple G-C-T nucleobase amino acid (NBA) building block featuring three recognition faces: DDA (G mimic), DAA (C mimic), and ADA (T mimic). Readily obtainable in multigram scale in a remarkably easy one-step reaction, this unique NBA building block offers scope for wide ranging applications for nucleic acid recognition and nucleic acid peptide/protein interaction studies.
Source
#1Jayanta Ghorai (Indian Institute of Technology Madras)H-Index: 6
#2Kuppan Ramachandran (Indian Institute of Technology Madras)H-Index: 2
Last. Pazhamalai Anbarasan (Indian Institute of Technology Madras)H-Index: 26
view all 3 authors...
A general and efficient rhodium-catalyzed redox-neutral annulation of N-acetoxyacetanilides, readily accessible from nitroarenes, with alkynes has been accomplished for the synthesis of substituted indole derivatives. A wide range of substituted 2,3-diarylindoles were achieved from various substituted N-acetoxyacetanilides and symmetrical/unsymmetrical alkynes in good to excellent yields. The developed method was successfully integrated with the synthesis of N-acetoxyacetanilides for the efficie...
Source
#1Jian Huang (Jiangxi Normal University)H-Index: 1
#2Wei Chen (Jiangxi Normal University)H-Index: 1
Last. Yiyuan Peng (Jiangxi Normal University)H-Index: 27
view all 7 authors...
A general and efficient method for the synthesis of quinazolinones, quinoxalinones, benzooxazinones, and benzothiazoles from the reactions of α-keto acids with 2-aminobenzamides, benzene-1,2-diamines, 2-aminophenols, and 2-aminobenzenethiols, respectively, is described. The reactions were conducted under catalyst-free conditions, using water as the sole solvent with no additive required, and successfully applied to the synthesis of sildenafil. More importantly, these reactions can be conducted o...
Source
#1Fengjuan Chen (SCUT: South China University of Technology)H-Index: 2
#2Xiang Huang (SCUT: South China University of Technology)
Last. Wei Zeng (SCUT: South China University of Technology)H-Index: 28
view all 5 authors...
A novel visible-light-induced coupling-cyclization of ortho-alkynylaryl vinylethers with arylsulfonyl azides has been described. This transformation provided a concise approach to access C3-exocyclic C═C bond/C2-alkylsulfone-tethered benzofurans via a solvent-leveraged carbosulfonylation and [2 + 2 + 3] cyclization. Primary mechanistic studies demonstrated that THF belongs to a crucial H atom source.
Source
#1Qinqin Xia (WMU: Wenzhou Medical College)
#2Shicheng Shi (RU: Rutgers University)H-Index: 19
Last. Michal Szostak (RU: Rutgers University)H-Index: 62
view all 6 authors...
We report the synthesis, characterization, and reactivity of [(NHC)PdCl2(aniline)] complexes. These well-defined, air- and moisture-stable catalysts are highly active in the Suzuki-Miyaura cross-coupling of amides by N-C(O) activation as well as in the Suzuki-Miyaura cross-coupling of esters, aryl chlorides, and Buchwald-Hartwig amination. Most crucially, this study introduces broadly available anilines as stabilizing ligands for well-defined Pd(II)-NHC catalysts. The availability of various ani...
Source
#1Hehuan Xu (Henan Normal University)H-Index: 1
#2Jiayu Liu (Henan Normal University)
Last. Zhiyong Jiang (Henan University)H-Index: 32
view all 5 authors...
An electrochemical hydropyridylation of thioester-activated alkenes with 4-cyanopyridines has been developed. The reactions experience a tandem electroreduction of both substrates on the cathode surface, protonation, and radical cross-coupling process, resulting in a variety of valuable pyridine variants, which contain a tertiary and even a quaternary carbon at the α-position of pyridines, in high yields. The employment of thioesters to the conjugated alkenes enables no requirement of catalyst a...
Source
#1Lidong Shan (THU: Tsinghua University)H-Index: 2
#2Hongchen Li (THU: Tsinghua University)
Last. Yuefei Hu (THU: Tsinghua University)H-Index: 22
view all 6 authors...
An efficient method for the synthesis of 6-alkynyl phenanthridines was developed. The method offered the first example to use 2-propynamides as substrates in the Bischler-Napieralski reaction and to create alkynylnitrilium triflates as new active intermediates in organic synthesis.
Source
#1Sebastian Ye (ANU: Australian National University)H-Index: 1
#2Martin G. Banwell (ANU: Australian National University)H-Index: 33
The enantiomerically pure, bromobenzene-derived metabolite 5 has been transformed into enone 20 using a reaction sequence involving Suzuki-Miyaura cross-coupling and Eschenmoser-Claisen rearrangement processes. Treatment of compound 20 with lithium hydroxide results in an acetonide fragmentation reaction that delivers the 4,4-disubstituted cyclohexa-2,5-dienone 21, reductive de-oxygenation of which leads to congener 22. A closely related sequence of reactions can be used to convert the same homo...
Source
#1Liqun Yang (SJTU: Shanghai Jiao Tong University)H-Index: 1
#2Jingyang Wang (SJTU: Shanghai Jiao Tong University)
Last. Xiaomin Xie (SJTU: Shanghai Jiao Tong University)H-Index: 16
view all 7 authors...
We report a highly efficient and selective catalytic system, ABNO (9-azabicyclo-[3.3.1]nonane N-oxyl)/HNO3, for the aerobic oxidation of substituted furans to cis-2-ene-1,4-diones under mild reaction conditions using oxygen as the oxidant. The catalyst system is amenable to various substituted (mon-, di-, and tri-) furans and tolerates diverse functional groups, including cyano, nitro, naphthyl, ketone, ester, heterocycle, and even formyl groups. Based on the control and 18O-labeling experiments...
Source
#1Ruby Krueger (WashU: Washington University in St. Louis)
#2Kevin D. Moeller (WashU: Washington University in St. Louis)H-Index: 39
Synthetic organic chemists are beginning to exploit electrochemical methods in increasingly creative ways. This is leading to a surge in productivity that is only now starting to take advantage of the full-potential of electrochemistry for accessing new structures in novel, more efficient ways. In this perspective, we provide insight into the potential of electrochemistry as a synthetic tool gained through studies of both direct anodic oxidation reactions and more recent indirect methods, and hi...
Source
12345678910
Top fields of study
Medicinal chemistry
Catalysis
Organic chemistry
Chemistry
Stereochemistry
Photochemistry