Renal tubule injury: a driving force toward chronic kidney disease.
Abstract
Renal tubules are the major component of the kidney and are vulnerable to a variety of injuries including hypoxia, proteinuria, toxins, metabolic disorders, and senescence. It has long been believed that tubules are the victim of injury. In this review, we shift this concept to renal tubules as a driving force in the progression of kidney diseases. In response to injury, tubular epithelial cells undergo changes and function as inflammatory and...
Paper Details
Title
Renal tubule injury: a driving force toward chronic kidney disease.
Published Date
Mar 1, 2018
Journal
Volume
93
Issue
3
Pages
568 - 579
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