pH sensitive methacrylated chitosan hydrogels with tunable physical and chemical properties

The pH of cutaneous wounds is dynamic and correlates with the stage of the wound healing process. The inflammation stage is acidic, granulation shifts to a progressively alkali pH, and the remodeling phase returns skin to its pre-injury pH. By taking the advantage of this pH difference, stage-specific wound treatments can be developed to respond to these environmental cues using pH sensitive hydrogels. To obtain tunable physical and chemical...