Original paper
Nitric oxide-releasing injectable hydrogels with high antibacterial activity through in situ formation of peroxynitrite
Abstract
Nitric oxide (NO) is an endogenous molecule with many critical biological functions that depend on its concentration. At high levels, NO provides broad-spectrum antibacterial effects through both its pathogen inhibition and killing abilities. However, its short half-life has been a great challenge to its clinical application in pharmaceutical forms. In this study, we incorporated the NO donor S-nitrosothiolated gelatin (GelSNO) into injectable...
Paper Details
Title
Nitric oxide-releasing injectable hydrogels with high antibacterial activity through in situ formation of peroxynitrite
Published Date
Dec 18, 2017
Journal
Volume
67
Pages
66 - 78
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Notes
History