Original paper
Pathways of Amyloid-β Aggregation Depend on Oligomer Shape
Volume: 140, Issue: 1, Pages: 319 - 327
Published: Dec 13, 2017
Abstract
One of the main research topics related to Alzheimer's disease is the aggregation of the amyloid-β peptide, which was shown to follow different pathways for the two major alloforms of the peptide, Aβ40 and the more toxic Aβ42. Experimental studies emphasized that oligomers of specific sizes appear in the early aggregation process in different quantities and might be the key toxic agents for each of the two alloforms. We use transition networks...
Paper Details
Title
Pathways of Amyloid-β Aggregation Depend on Oligomer Shape
Published Date
Dec 13, 2017
Volume
140
Issue
1
Pages
319 - 327