Substance P prevents development of proliferative vitreoretinopathy in mice by modulating TNF-α.
Abstract
Proliferative vitreoretinopathy (PVR) is an inflammatory fibrotic disease resulting from the inflammatory milieu after retinal detachment, which can prevent retinal healing. This study aimed to elucidate the effect of substance P (SP) on retinal degeneration caused by retinal detachment in vivo and to examine the role of SP in the tumor necrosis factor-alpha (TNF-α)-induced epithelial-mesenchymal transition (EMT) of human RPE cells in...
Paper Details
Title
Substance P prevents development of proliferative vitreoretinopathy in mice by modulating TNF-α.
Published Date
Jan 1, 2017
Journal
Volume
23
Pages
933 - 943
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Notes
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