Relaxivity of Ferumoxytol at 1.5 T and 3.0 T

Objectives The aim of this study was to determine the relaxation properties of ferumoxytol, an off-label alternative to gadolinium-based contrast agents, under physiological conditions at 1.5 T and 3.0 T. Materials and Methods Ferumoxytol was diluted in gradually increasing concentrations (0.26–4.2 mM) in saline, human plasma, and human whole blood. Magnetic resonance relaxometry was performed at 37°C at 1.5 T and 3.0 T. Longitudinal and...